Cachexia, Insulin resistance: results from ‘metabolic syndrome’ and also from exposure to IMPL2 protein secreted by cancer cells

I’m just connecting things together.

There is ‘metabolic syndrome.’ You get insulin resistance and Type 2 diabetes, for whatever reason. But this is usually associated with being fat.

Cachexia: When you get cancer, you waste away. Cancer tumors secrete IMPL2, a protein that prevents other cells from using sugar, which is for all practical purposes insulin resistance (says an article in the google results).

What is the connection between metabolic syndrome and cancer tumors? How are they similar? Are there any ways to treat or fix metabolic syndrome that will also be helpful for treating cancer? Do insights into the one also apply to the other?

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